Italian Sub

By Laurel Perry

Published Jun 9, 2025

In my humble opinion, there’s no better lunch than a classic Italian sub sandwich. A hefty sub roll stuffed to the brim with all of my favorite Italian deli meats, Provolone cheese, lettuce, tomatoes, onions, Peperoncino, and a tangy dressing to tie it all together is just chef’s kiss! Plus, it’s just so much more economical to make this sandwich at home, and I love that I can make mini-subs for my kids since even the small ones from my local sub shop are way too big for them.

overhead view of an italian sub on parchment paper. - 5

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Homemade Italian Sub

Subway can’t hold a candle to this homemade Italian sub recipe. It’s absolutely packed with 3 types of meat and creamy Provolone cheese. My secret weapon is my Italian sub dressing, which is a simple mix of oil vinegar, jarred Italian seasoning, and Dijon mustard– so simple, and so delicious!

Tips for Beginners

It’s all about the bread! Make sure to choose a roll that can really stand up to all the filling.
I like to vary the meats according to my mood. Some other deli meats I love include hot capicola, mortadella, and prosciutto.
Opt for freshly sliced cold cuts over the pre-packaged kind whenever possible. That way, you can get it sliced to your preferred thickness (the thinner, the better!) and it will be guaranteed fresh.
After assembling, gently press down on the sandwich to hold everything together. I like to wrap mine in parchment paper or aluminum foil for extra protection.

Ingredients1x2x3x

▢ 4 hoagie rolls
▢ 8 tablespoons mayonnaise
▢ 4 ounces Genoa salami
▢ 4 ounces pepperoni
▢ 8 ounces roasted turkey breast
▢ 6 ounces Provolone cheese
▢ 2 cups shredded iceberg lettuce
▢ 1-2 medium tomatoes sliced
▢ 1 red onion thinly sliced
▢ ¼ cup sliced pepperoncini peppers or cherry peppers

For the Dressing

▢ 3 tablespoons extra virgin olive oil
▢ 2 tablespoons red wine vinegar
▢ 2 teaspoons Italian seasoning
▢ 1 teaspoon Dijon mustard

Video

Instructions

Spread 2 tablespoons of mayonnaise on the bottom of each roll. 4 hoagie rolls, 8 tablespoons mayonnaise
Top with salami, pepperoni, turkey, and provolone cheese. 4 ounces Genoa salami, 4 ounces pepperoni, 8 ounces roasted turkey breast, 6 ounces Provolone cheese
To the top half of the roll, layer on the lettuce, tomato, red onion, and pepperoncini peppers. 2 cups shredded iceberg lettuce, 1-2 medium tomatoes, 1 red onion, ¼ cup sliced pepperoncini peppers
In a small bowl, whisk together the olive oil, red wine vinegar, dried Italian seasoning, and dijon mustard until completely combined and creamy. 3 tablespoons extra virgin olive oil, 2 tablespoons red wine vinegar, 2 teaspoons Italian seasoning, 1 teaspoon Dijon mustard
Drizzle this over the top half (the vegetable side) of each sandwich. Bring the two halves together and enjoy immediately.

Nutrition information is automatically calculated, so should only be used as an approximation.

How to Make an Italian Sub Step by Step

the bottom half of an open sub roll slathered with mayonnaise. - 6

Spread the Mayo: Spread 2 tablespoons of mayonnaise on the bottom of each of 4 hoagie rolls.

meats and cheeses layered on the bottom half of a sub roll. - 7

Layer the Meats: Top each with 1 ounce of Genoa salami, 1 ounce of pepperoni, 2 ounces of roasted turkey breast, and 1½ ounces of Provolone cheese.

meats, cheeses, lettuce, tomato, red onion, and pepperoncini layered on the bottom half of a sub roll. - 8

Add the Veggies: To the top half of the roll, layer on ½ cup of shredded lettuce, ¼-½ of a sliced tomato, ¼ of a sliced red onion, and 1 tablespoon of pepperoncini peppers.

italian seasoned sub dressing in a glass bowl. - 9

Mix the Dressing: In a small bowl, whisk together 3 tablespoons of extra virgin olive oil, 2 tablespoons of red wine vinegar, 2 teaspoons of Italian seasoning, and 1 teaspoon of Dijon mustard until completely combined and creamy.

an open italian sub on parchment paper. - 10

Drizzle: Drizzle this over the top half (the vegetable side) of each sandwich.

italian sub sandwiches on parchment paper. - 11

Serve: Bring the two halves together and enjoy immediately.

Serving Suggestions

There’s nothing better with a classic Italian sub than some chips and a soda. I love these homemade sweet potato chips ! Some french fries or potato salad would also be delish!

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